The short answer? No. The long answer…
The way we run elections is so familiar that it's hard to imagine any other way to do it. You look at a list of options, you choose the name that you want, and the person with the most votes wins—that's how you vote, right?
If you do a little research, though, you'll discover that there are a lot of ways you can run an election, some with names like "ranked voting" or "single transferrable vote." Many of these systems work very differently from what we're used to.
Including a "none of the above" option is actually one of the least radical changes we could make to our elections. It doesn't take away any choices that are already available, and it doesn't have to change how votes are counted.
It's also not a new idea. Since 1975, all state-wide elections in Nevada (including President and Vice President) have featured a "None of the Candidates" option; the state actually changed its laws to require the option (read about it in this Washington Post story).
In addition to Nevada, several countries either currently have or used to have a ballot option equivalent to "none of the above." Individual candidates and whole parties dedicated to NOTA idea also exist.